Timothy J. Vyse: search on Z-Library

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1

Expansion of circulating T cells resembling follicular helper T cells is a fixed phenotype that identifies a subset of severe systemic lupus erythematosus

Nicholas Simpson, Paul A. Gatenby, Anastasia Wilson, Shreya Malik, David A. Fulcher, Stuart G. Tangye, Harinder Manku, Timothy J. Vyse, Giovanna Roncador, Gavin A. Huttley, Christopher C. Goodnow, Car

Journal:

Arthritis & Rheumatism

Year:

2010

Language:

english

File:

PDF, 785 KB

english, 2010

2

Models of systemic lupus erythematosus

Robert J. Rigby, Timothy J. Vyse

Journal:

Drug Discovery Today: Disease Models

Year:

2004

Language:

english

File:

PDF, 119 KB

english, 2004

3

Meta-analysis of GWAS on both Chinese and European populations identifies GPR173 as a novel X chromosome susceptibility gene for SLE

Zhang, Huoru, Zhang, Yan, Wang, Yong-Fei, Morris, David, Hirankarn, Nattiya, Sheng, Yujun, Shen, Jiangshan, Pan, Hai-Feng, Yang, Jing, Yang, Sen, Cui, Yong, Ye, Dong-Qing, Vyse, Timothy J., Zhang, Xue

Journal:

Arthritis Research & Therapy

Year:

2018

Language:

english

File:

PDF, 587 KB

english, 2018

4

The Genetics of SystemicLupus erythe matosus

Roberton, Cheri A., Vyse, Timothy J.

Journal:

Nephron Experimental Nephrology

Year:

2000

Language:

english

File:

PDF, 332 KB

english, 2000

5

Evidence for both copy number and allelic (NA1/NA2) risk at the FCGR3B locus in systemic lupus erythematosus

Morris, David L, Roberts, Amy L, Witherden, Abigail S, Tarzi, Ruth, Barros, Paula, Whittaker, John C, Cook, Terence H, Aitman, Timothy J, Vyse, Timothy J

Journal:

European Journal of Human Genetics

Year:

2010

Language:

english

File:

PDF, 335 KB

english, 2010

6

Sa.54. Positional Identification of Integrin- αMβ2 (ITGAM) as a Susceptibility Gene for Systematic Lupus Erythematosus (SLE)

Swapan Nath, Shizhong Han, Xana Kim-Howard, Harshal Deshmukh, Parvathi Viswanathan, Gail Bruner, Jennifer Kelly, Gary Gilkeson, Rodger McEver, Robert Kimberly, Timothy Vyse, Wei Chen, Cheng Zhu, Marta

Journal:

Clinical Immunology

Year:

2008

Language:

english

File:

PDF, 61 KB

english, 2008

7

Resequencing the susceptibility gene,ITGAM, identifies two functionally deleterious rare variants in systemic lupus erythematosus cases

Roberts, Amy L, Thomas, Ellen RA, Bhosle, Shriram, Game, Laurence, Obraztsova, Olga, Aitman, Timothy J, Vyse, Timothy J, Rhodes, Benjamin

Journal:

Arthritis Research & Therapy

Year:

2014

Language:

english

File:

PDF, 505 KB

english, 2014

8

Autophagy is activated in systemic lupus erythematosus and required for plasmablast development

Clarke, Alexander J, Ellinghaus, Ursula, Cortini, Andrea, Stranks, Amanda, Simon, Anna Katharina, Botto, Marina, Vyse, Timothy J

Journal:

Annals of the Rheumatic Diseases

Year:

2015

Language:

english

File:

PDF, 2.86 MB

english, 2015

9

Hyper IgE in New Zealand black mice due to a dominant-negative CD23 mutation

Graham Lewis, Eleni Rapsomaniki, Tiphaine Bouriez, Tanya Crockford, Helen Ferry, Robert Rigby, Timothy Vyse, Teresa Lambe, Richard Cornall

Journal:

Year:

2004

Language:

english

File:

PDF, 244 KB

english, 2004

10

The Wolf at the Door

Uttenthal, Benjamin J., Layton, D. Mark, Vyse, Timothy J., Schreiber, Benjamin E.

Journal:

New England Journal of Medicine

Year:

2012

Language:

english

File:

PDF, 578 KB

english, 2012

11

Using genetics to deliver personalized SLE therapy—a realistic prospect?

Rhodes, Benjamin, Vyse, Timothy J.

Journal:

Nature Reviews Rheumatology (formerly Nature Clinical Practice Rheumatology)

Year:

2010

Language:

english

File:

PDF, 210 KB

english, 2010

12

A Major Histocompatibility Class I Locus Contributes to Multiple Sclerosis Susceptibility Independently from HLA-DRB1*15:01

Cree, Bruce A. C., Rioux, John D., McCauley, Jacob L., Gourraud, Pierre-Antoine F. D., Goyette, Philippe, McElroy, Joseph, De Jager, Philip, Santaniello, Adam, Vyse, Timothy J., Gregersen, Peter K., M

Journal:

Year:

2010

Language:

english

File:

PDF, 441 KB

english, 2010

13

Copy number polymorphism in Fcgr3 predisposes to glomerulonephritis in rats and humans

Aitman, Timothy J., Dong, Rong, Vyse, Timothy J., Norsworthy, Penny J., Johnson, Michelle D., Smith, Jennifer, Mangion, Jonathan, Roberton-Lowe, Cheri, Marshall, Amy J., Petretto, Enrico

Journal:

Year:

2006

Language:

english

File:

PDF, 366 KB

english, 2006

14

UBE2L3 Polymorphism Amplifies NF-κB Activation and Promotes Plasma Cell Development, Linking Linear Ubiquitination to Multiple Autoimmune Diseases

Lewis, Myles J., Vyse, Simon, Shields, Adrian M., Boeltz, Sebastian, Gordon, Patrick A., Spector, Timothy D., Lehner, Paul J., Walczak, Henning, Vyse, Timothy J.

Journal:

The American Journal of Human Genetics

Year:

2015

Language:

english

File:

PDF, 1.85 MB

english, 2015

15

What does the immunogenetic basis of rheumatoid arthritis teach us about the immunobiology of the disease?

Gorman, Claire, Vyse, Timothy, Cope, Andrew

Journal:

Expert Review of Clinical Immunology

Year:

2006

Language:

english

File:

PDF, 707 KB

english, 2006

16

Genetic advances in systemic lupus erythematosus

Chen, Lingyan, Morris, David L., Vyse, Timothy J.

Journal:

Current Opinion in Rheumatology

Year:

2017

Language:

english

File:

PDF, 869 KB

english, 2017

17

[Lupus Foundation of America 13th International Congress on Systemic Lupus Erythematosus (LUPUS 2019), San Francisco, California, USA, April 5â8, 2019, Abstract Presentations - ()] Abstracts - 240âTrans-ancestral exclusion mapping strategy prioritises risk alleles at IKZF3 with increased biological relevance

Cunninghame Graham, Deborah S, Vyse, Timothy

Year:

2019

File:

PDF, 68 KB

2019

18

Mutations in the gene encoding the 3′-5′ DNA exonuclease TREX1 are associated with systemic lupus erythematosus

Lee-Kirsch, Min Ae, Gong, Maolian, Chowdhury, Dipanjan, Senenko, Lydia, Engel, Kerstin, Lee, Young-Ae, de Silva, Udesh, Bailey, Suzanna L, Witte, Torsten, Vyse, Timothy J

Journal:

Nature Genetics

Year:

2007

Language:

english

File:

PDF, 263 KB

english, 2007

19

Defining the Role of the MHC in Autoimmunity: A Review and Pooled Analysis

Fernando, Michelle M. A., Stevens, Christine R., Walsh, Emily C., De Jager, Philip L., Goyette, Philippe, Plenge, Robert M., Vyse, Timothy J., Rioux, John D., Fisher, Elizabeth M. C.

Journal:

Year:

2008

Language:

english

File:

PDF, 260 KB

english, 2008

20

Association of NCF2, IKZF1, IRF8, IFIH1, and TYK2 with Systemic Lupus Erythematosus

Cunninghame Graham, Deborah S., Morris, David L., Bhangale, Tushar R., Criswell, Lindsey A., Syvänen, Ann-Christine, Rönnblom, Lars, Behrens, Timothy W., Graham, Robert R., Vyse, Timothy J., McCarthy,

Journal:

Year:

2011

Language:

english

File:

PDF, 686 KB

english, 2011

21

A defunctioning polymorphism inFCGR2Bis associated with protection against malaria but susceptibility to systemic lupus erythematosus

Lisa C. Willcocks, Edward J. Carr, Heather A. Niederer, Tim F. Rayner, Thomas N. Williams, Wanling Yang, J. Anthony G. Scott, Britta C. Urban, Norbert Peshu, Timothy J. Vyse, Yu Lung Lau, Paul A. Lyon

Journal:

Proceedings of the National Academy of Sciences

Year:

2010

Language:

english

File:

PDF, 1.04 MB

english, 2010

22

Trans-Ancestral Fine-Mapping and Epigenetic Annotation as Tools to Delineate Functionally Relevant Risk Alleles at IKZF1 and IKZF3 in Systemic Lupus Erythematosus

Vyse, Timothy J., Cunninghame Graham, Deborah S.

Journal:

International Journal of Molecular Sciences

Year:

2020

File:

PDF, 4.50 MB

2020

23

Genetically Determined Partial Complement C4 Deficiency States Are Not Independent Risk Factors for SLE in UK and Spanish Populations

Lora Boteva, David L. Morris, Josefina Cortés-Hernández, Javier Martin, Timothy J. Vyse, Michelle M.A. Fernando

Journal:

The American Journal of Human Genetics

Year:

2012

Language:

english

File:

PDF, 380 KB

english, 2012

24

A defunctioning polymorphism in FCGR2B is associated with protection against malaria but susceptibility to systemic lupus erythematosus

Willcocks, Lisa C., Carr, Edward J., Niederer, Heather A., Rayner, Tim F., Williams, Thomas N., Yang, Wanling, Scott, J. Anthony G., Urban, Britta C., Peshu, Norbert, Vyse, Timothy J., Lau, Yu Lung, L

Journal:

Proceedings of the National Academy of Sciences

Year:

2010

Language:

english

File:

PDF, 162 KB

english, 2010

25

A Genetic Association Study of Serum Acute-Phase C-Reactive Protein Levels in Rheumatoid Arthritis: Implications for Clinical Interpretation

Rhodes, Benjamin, Merriman, Marilyn E., Harrison, Andrew, Nissen, Michael J., Smith, Malcolm, Stamp, Lisa, Steer, Sophia, Merriman, Tony R., Vyse, Timothy J., Hingorani, Aroon

Journal:

Year:

2010

Language:

english

File:

PDF, 272 KB

english, 2010

26

Improved monitoring of clinical response in Systemic Lupus Erythematosus by longitudinal trend in soluble vascular cell adhesion molecule-1

Lewis, Myles J., Vyse, Simon, Shields, Adrian M., Zou, Lu, Khamashta, Munther, Gordon, Patrick A., Pitzalis, Costantino, Vyse, Timothy J., D’Cruz, David P.

Journal:

Arthritis Research & Therapy

Year:

2016

Language:

english

File:

PDF, 788 KB

english, 2016

27

The Complement Receptor 3 (CD11b/CD18) agonist Leukadherin-1 suppresses human innate inflammatory signalling

Roberts, Amy L., Fürnrohr, Barbara G., Vyse, Timothy J., Rhodes, Benjamin

Journal:

Clinical & Experimental Immunology

Year:

2016

Language:

english

File:

PDF, 1.57 MB

english, 2016

28

Family-based association analysis with ordered categorical phenotypes, covariates and interactions

M. Fazil Baksh, David J. Balding, Timothy J. Vyse, John C. Whittaker

Journal:

Genetic Epidemiology

Year:

2007

Language:

english

File:

PDF, 138 KB

english, 2007

29

Investigation of the HIN200 Locus in UK SLE Families Identifies Novel Copy Number Variants

Michelle M. A. Fernando, Adam J. de Smith, Lachlan Coin, David L. Morris, Philippe Froguel, Jonathan Mangion, Alexandra I. F. Blakemore, Robert R. Graham, Timothy W. Behrens, Timothy J. Vyse

Journal:

Annals of Human Genetics

Year:

2011

Language:

english

File:

PDF, 945 KB

english, 2011

30

Haplotype structure of TNFRSF5-TNFSF5 (CD40–CD40L) and association analysis in systemic lupus erythematosus

Chadha, Sapna, Miller, Katie, Farwell, Lisa, Lightstone, Liz B, Daly, Mark J, Rioux, John D, Vyse, Timothy J

Journal:

European Journal of Human Genetics

Year:

2005

Language:

english

File:

PDF, 188 KB

english, 2005

31

Sa.9. Common Variants within MECP2 Confer Risk of Systemic Lupus Erythematosus

Amr Sawalha, Ryan Webb, Shizhong Han, Jennifer Kelly, Kenneth Kaufman, Robert Kimberly, Marta Alarcón-Riquelme, Judith James, Timothy Vyse, Gary Gilkeson, Chan-Bum Choi, Hal Scofield, Sang-Cheol Bae,

Journal:

Clinical Immunology

Year:

2008

Language:

english

File:

PDF, 53 KB

english, 2008

32

The Molecular Basis by Which Polymorphism in the OX40L Gene Predisposes to SLE

Harinder Manku, Deborah Cunninghame Graham, Robert R. Graham, Timothy W. Behrens, Timothy W. Behrens, David Althshuler, Timothy J. Vyse

Journal:

Clinical Immunology

Year:

2007

Language:

english

File:

PDF, 44 KB

english, 2007

33

Thymic Microenvironment and NZB Mice: The Abnormal Thymic Microenvironment of New Zealand Mice Correlates with Immunopathology

Yuichi Takeoka, Nobuhisa Taguchi, Brian L. Kotzin, Sean Bennett, Timothy J. Vyse, Richard L. Boyd, Mitsuru Naiki, Jin-emon Konishi, Aftab A. Ansari, Leonard D. Shultz, M.Eric Gershwin

Journal:

Clinical Immunology

Year:

1999

Language:

english

File:

PDF, 173 KB

english, 1999

34

Accelerated exposure of phosphatidylserine on lymphocyte populations from patients with systemic lupus erythematosus or rheumatoid arthritis

Albrecht, Christiane, Soumian, Soni, Playford, Raymond, Higgins, Christopher, Vyse, Timothy, Elliott, James

Journal:

Thrombosis and Haemostasis

Year:

2005

Language:

english

File:

PDF, 512 KB

english, 2005

35

Genome-wide association scan in women with systemic lupus erythematosus identifies susceptibility variants in ITGAM, PXK, KIAA1542 and other loci

Harley, John B, Alarcón-Riquelme, Marta E, Criswell, Lindsey A, Jacob, Chaim O, Kimberly, Robert P, Moser, Kathy L, Tsao, Betty P, Vyse, Timothy J, Langefeld, Carl D

Journal:

Nature Genetics

Year:

2008

Language:

english

File:

PDF, 344 KB

english, 2008

36

The genetics of lupus: a functional perspective

Sandra G Guerra,Timothy J Vyse…

Journal:

Arthritis Research & Therapy

Year:

2012

Language:

english

File:

PDF, 447 KB

english, 2012

37

Spontaneous Autoimmunity in 129 and C57BL/6 Mice—Implications for Autoimmunity Described in Gene-Targeted Mice

Bygrave, Anne E., Rose, Kirsten L., Cortes-Hernandez, Josefina, Warren, Joanna, Rigby, Robert J., Cook, H. Terence, Walport, Mark J., Vyse, Timothy J., Botto, Marina

Journal:

Year:

2004

Language:

english

File:

PDF, 205 KB

english, 2004

38

Dysregulated CD46 shedding interferes with Th1-contraction in systemic lupus erythematosus

Ellinghaus, Ursula, Cortini, Andrea, Pinder, Christopher L., Friec, Gaelle Le, Kemper, Claudia, Vyse, Timothy J.

Journal:

European Journal of Immunology

Year:

2017

Language:

english

File:

PDF, 1.77 MB

english, 2017

39

Contrasting genetic association ofIL2RAwith SLE and ANCA – associated vasculitis

Edward J Carr, Menna R Clatworthy, Christopher E Lowe, John A Todd, Andrew Wong, Timothy J Vyse, Lavanya Kamesh, Richard A Watts, Paul A Lyons, Kenneth GC Smith

Journal:

BMC Medical Genetics

Year:

2009

Language:

english

File:

PDF, 543 KB

english, 2009

40

Profiling RNA-Seq at multiple resolutions markedly increases the number of causal eQTLs in autoimmune disease

Odhams, Christopher A., Cunninghame Graham, Deborah S., Vyse, Timothy J., Lappalainen, Tuuli

Journal:

Year:

2017

Language:

english

File:

PDF, 6.65 MB

english, 2017

41

Association of the co-stimulator OX40L with systemic lupus erythematosus

Harinder Manku, Deborah S. Cunninghame Graham, Timothy J. Vyse

Journal:

Journal of Molecular Medicine

Year:

2009

Language:

english

File:

PDF, 298 KB

english, 2009

42

Large-Scale Identification of Common Trait and Disease Variants Affecting Gene Expression

Hauberg, Mads Engel, Zhang, Wen, Giambartolomei, Claudia, Franzén, Oscar, Morris, David L., Vyse, Timothy J., Ruusalepp, Arno, Sklar, Pamela, Schadt, Eric E., Björkegren, Johan L.M., Roussos, Panos, F

Journal:

The American Journal of Human Genetics

Year:

2017

Language:

english

File:

PDF, 1.41 MB

english, 2017

43

Independent Replication on Genome-Wide Association Study Signals Identifies IRF3 as a Novel Locus for Systemic Lupus Erythematosus

Zhang, Feixia, Wang, Yong-Fei, Zhang, Yan, Lin, Zhiming, Cao, Yujie, Zhang, Huoru, Liu, Zhong-Yi, Morris, David L., Sheng, Yujun, Cui, Yong, Zhang, Xuejun, Vyse, Timothy J., Lau, Yu Lung, Yang, Wanlin

Journal:

Frontiers in Genetics

Year:

2020

File:

PDF, 801 KB

2020

44

Identification of ST3AGL4 , MFHAS1, CSNK2A2 and CD226 as loci associated with systemic lupus erythematosus (SLE) and evaluation of SLE genetics in drug repositioning

Wang, Yong-Fei, Zhang, Yan, Zhu, Zhengwei, Wang, Ting-You, Morris, David L, Shen, Jiangshan Jane, Zhang, Huoru, Pan, Hai-Feng, Yang, Jing, Yang, Sen, Ye, Dong-Qing, Vyse, Timothy J, Cui, Yong, Zhang,

Journal:

Annals of the Rheumatic Diseases

Year:

2018

Language:

english

File:

PDF, 1.72 MB

english, 2018

45

B cell OX40L supports T follicular helper cell development and contributes to SLE pathogenesis

Cortini, Andrea, Ellinghaus, Ursula, Malik, Talat H, Cunningham Grahman, Deborah S, Botto, Marina, Vyse, Timothy James

Journal:

Annals of the Rheumatic Diseases

Year:

2017

Language:

english

File:

PDF, 2.82 MB

english, 2017

46

Assessment of complement C4 gene copy number using the paralog ratio test

Michelle M.A. Fernando, Lora Boteva, David L. Morris, Bi Zhou, Yee Ling Wu, Marja-Liisa Lokki, Chack Yung Yu, John D. Rioux, Edward J. Hollox, Timothy J. Vyse

Journal:

Year:

2010

Language:

english

File:

PDF, 388 KB

english, 2010

47

Evidence for an Interferon-Inducible Gene, Ifi202, in the Susceptibility to Systemic Lupus

Stephen J Rozzo, John D Allard, Divaker Choubey, Timothy J Vyse, Shozo Izui, Gary Peltz, Brian L Kotzin

Journal:

Year:

2001

Language:

english

File:

PDF, 183 KB

english, 2001

48

Large-Scale Identification of Common Trait and Disease Variants Affecting Gene Expression

Hauberg, Mads Engel, Zhang, Wen, Giambartolomei, Claudia, Franzén, Oscar, Morris, David L., Vyse, Timothy J., Ruusalepp, Arno, Sklar, Pamela, Schadt, Eric E., Björkegren, Johan L.M., Roussos, Panos, F

Journal:

The American Journal of Human Genetics

Year:

2017

File:

PDF, 33 KB

2017

49

Selective IgA Deficiency in Autoimmune Diseases

Wang, Ning, Shen, Nan, Vyse, Timothy J., Anand, Vidya, Gunnarson, Iva, Sturfelt, Gunnar, Rantapää-Dahlqvist, Solbritt, Elvin, Kerstin, Truedsson, Lennart, Andersson, Bengt A., Dahle, Charlotte, Örtqvi

Journal:

Molecular Medicine

Year:

2011

Language:

english

File:

PDF, 1.17 MB

english, 2011

50

Analysis of systemic lupus erythematosus sub-phenotype data for genetic association

Morris, David L., Vyse, Timothy J.

Journal:

Current Opinion in Rheumatology

Year:

2012

Language:

english

File:

PDF, 1.51 MB

english, 2012

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